Minnesota was held to just four hits in each of the first two games of its series against Seattle, but the Twins smashed six home runs in a 10-4 win on Sunday afternoon. Catcher Gary Sanchez hit a first-inning grand slam that was the exclamation point, giving the Twins an opportunity to salvage the series. They are -130 favorites (risk $130 to win $100) to win the final game of the four-game set at 7:40 p.m. ET on Monday night, according to the latest 2022 MLB odds at Caesars Sportsbook. Seattle has an opportunity to start the season with a 3-1 record heading into a tough slate of games against the White Sox and Astros.
Meanwhile, San Diego dropped its season-opener at Arizona, but it responded with three straight wins to take the series. The Padres will try to build on that momentum when they travel to San Francisco for a three-game series that begins at 9:45 p.m. ET on Monday night. Before locking in any MLB picks or parlays, be sure to check out the MLB predictions and betting advice from SportsLine's proven computer model.
This model, which simulates every game 10,000 times, enters Week 2 of the 2022 season on a 216-181 roll on top-rated MLB money-line picks that dates back to last season, returning over $900 for $100 players. Anyone following it has seen huge returns.
Now, the model has locked in four confident MLB best bets for Monday night. They all involve games after 7:20 p.m. ET, so there's still time to get these MLB picks in. If you successfully parlay the picks, you'd be looking at a payout of more than 10-1. You can see the model's MLB picks for Monday only at SportsLine.
Top MLB picks today
After simulating each of Monday's games 10,000 times, the model is backing the over 9.5 runs (+100) in the Braves vs. Nationals matchup. This contest features a pair of offenses that ranked inside the top 10 in the MLB in team batting average last season. Atlanta replaced long-time first baseman Freddie Freeman with Matt Olson, who had eight hits in four games against Cincinnati over the weekend. Austin Riley added five hits in 13 at-bats, putting his batting average at .385 to open the season.
Washington's lineup features one of the best hitters on the planet in Juan Soto, who is joined by hard-hitting first baseman Josh Bell. Both players went yard in their season-opening series against the Mets. Neither of these starting pitchers are reliable, so this should be a high-scoring game. The model has the over hitting in 69 percent of simulations, showing a combined run total of 9.8.
How to make MLB parlays for Monday
The model also locked in three other best bets for Monday, including a road underdog that is winning in well over 50 percent of simulations. You can only see the model's MLB parlay picks and best bets for Monday at SportsLine.
What MLB picks should you target for a payout of more than 10-1? And what road underdog is the model strongly backing on Monday? Visit SportsLine now to see the MLB best bets for Monday from a model that has a 216-181 record on top-rated MLB money-line picks dating back to 2021, and find out.
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